https://www.raspberrypi.com/products/rp2350/
From postings, I know that folks use the RP2350 for interfacing; the trade press has been
shipping news of RP's rev A4 datasheet in volume.
The datasheet should tell all. However, the 5V tollerance of the "IO" pins is
significant for its simplification of TTL interfacing; the maximum supply and output
voltage remains 3v3. See section 14.8.2 (p 1335) et seq - NB the FT indication.
Martin